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Introduction of Noopept

A new generation of nootropics? Noopept is a nootropic peptide developed and prescribed in Russia. It is derived from the racetam family of compounds and has a common mechanism of action but is purported to be up to 1000 times more potent than piracetam – being the most popular and most researched nootropic of our generation.


Part of the Ampakine sub-class, the Racetam family of nootropics work in part by binding to glutamate receptors. This augments the neurotransmitter glutamate and enables the more fluent encoding of memory and hence significantly boosts learning capacity. However the Racetam family have only weak to moderate AMPA modulation, and possess many different mechanisms of action. Noopept can lead to:

•Increased creativity
•Improved mood
•Reduced stress
•Augmented levels of focus and motivation
•Higher levels of verbal acuity (I particularly notice this)
•Higher self-esteem (as everything seems easier)


The majority of researchers recommend noopept be taken sublingually, and it is my opinion that this advice should be adhered to (I have experienced the most positive effects) Dosing varies anywhere from 10mg-30mg three times daily, I would strongly advise against mega-dosing as several negative side effects can occur (irritation, sedation, emotional numbness) You may wish to have a chaser at the ready as this chemical tastes like paracetamol made by the devil.


I have taken noopept extensively and would highly recommend it as a nootropic compound. With minimal dosing I enjoy improved creativity, confidence and verbal acuity. Negatively I am quite confident that noopept reduces my libido and without an obvious mechanism for this effect, more study is warranted to quantify its safety.