Comments Off on Oxiracetam

Oxiracetam is a nootropic in the racetam family. It is, like piracteam, water soluble. Oxiracetam is slightly more potent than piracetam, but significantly less potent than aniracetam and pramiracetam. Oxiracetam is largely under-reported due to its “middle ground” effects as a nootropic, but it should not be discounted.

Mechanism of Action

Oxiracteam acts in the same way that all other racetam analogues act. The prevalent hypothesis is that racetams interact with glutamate neurotransmission, reinforcing the neurotransmitter glutamate and promoting an increase in the quality of memory encoding, thus increasing learning capacity. Racetams also recruit AMPA receptors that would not normally be part of synaptic transmissions. It should be noted that the racetam family possess a variety of other mechanisms, as well as only having weak to moderate AMPA modulation. Much like other racetams, oxiracteam has a low toxicity level and is considered very safe.


Oxiracetam promotes learning and memory in the same way as other racetams.


One study suggests that a dose between 1200 mg and 2400 mg daily offers the most noticeable effects.